As the distance of the interincisor opening was gradually increased, the canine was strongly loaded in case of the TheraBite^® appliance.
When the interincisor opening distance reached 10.4 mm, the central and lateral incisors were loaded mainly in the shell-shaped mouth opening appliance.
Furthermore, as the distance of the interincisor opening was gradually increased, the canine and first premolars were gradually loaded.