cdk4 | p16 | ||||
---|---|---|---|---|---|
Cytoplasmic | Nuclear | Cytoplasmic | Nuclear | ||
Oral lichen planus | Cases with positive staining/total no. (%) | 48/60 (80) | 19/60 (31.7) | 41/60 (68.3) | 11/60 (18.3) |
Mean of % no. of cells stained (SD) Median (range) |
19.6 (22) | 3 (7.5) | 16.4 (22.6) | 3.9 (13) | |
11 (0 - 80) | 0 (0 - 42) | 5 (0 - 90) | 0 (0 - 65) | ||
Negative control (normal mucosa) |
Cases with positive staining/total no. (%) P-valuea |
0/10 (0) | 4/10 (40) | 0/10 (0) | 0/10 (0) |
0.0001 | 0.06 | 0.0002 | 0.31 | ||
Mean of % no. of cells stained (SD) Median (range) P-valueb |
0 (0) | 1.3 (0.2) | 0 (0) | 0 (0) | |
0 (0 - 0) | 0 (0 - 4) | 0 (0 - 0) | 0 (0 - 0) | ||
0.0001 | 0.17 | < 0.0001 | 0.16 | ||
Positive control (OSCC) |
Cases with positive staining/total no. (%) P-valuea |
10/10 (100) | 10/10 (100) | 10/10 (100) | 10/10 (100) |
0.23 | 0.0001 | 0.03 | 0.0001 | ||
Mean of % no. of cells stained (SD) Median (range) P-valueb |
74 (6.8) | 74 (6.8) | 80.9 (3.1) | 80.9 (3.1) | |
74 (65 - 83) | 74 (65 - 83) | 81 (75 - 85) | 81 (75 - 85) | ||
< 0.001 | < 0.001 | < 0.001 | < 0.001 |
aP value between oral lichen planus and normal mucosa group, Pearson Chi Square test.
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