Component Description
Population Patients included in clinical studies that evaluate the effect of materials containing fluoride and/or casein phosphopeptide-amorphous calcium phosphate on the WSLs during and after fixed orthodontic treatment.
Intervention Use of materials containing fluoride and/or casein phosphopeptide-amorphous calcium phosphate on the WSLs on patients with fixed appliances.
Comparison Remineralization effect of materials containing fluoride and/or casein phosphopeptide-amorphous calcium phosphate on the WSLs.
Outcome Changes in the development of new WSLs and improvement of WSLs appearance while using materials containing fluoride and/or casein phosphopeptide-amorphous calcium phosphate.
Study design Randomized and non-randomized controlled trials, cohort studies.