Study Year of
publication 		Type of study Reason of exclusion
Kostantinidis et al. [6] 2015 Cross sectional Not prospective
Casado et al. [27] 2013 Retrospective Not prospective
Marrone et al. [29] 2013 Cross-sectional Not prospective
Roccuzzo et al. [30] 2014 Prospective Did not compare smokers vs. no smokers
Swierkot et al. [33] 2012 Prospective Did not compare smokers vs. no smokers
Roos-Jansåker [34] 2006 Prospective Did not compare smokers vs. no smokers
Costa et al. [35] 2012 Follow up study Did not report information on smoking
Dvorak et al. [36] 2011 Cross sectional Not prospective
Schropp et al. [37] 2014 Randomized clinical trial Did not compare smokers vs. no smokers
Göthberg et al. [38] 2014 Randomized clinical trial Did not report information on peri-implantitis
Sanz et al. [39] 2015 Randomized clinical trial Did not report information on smoking
Cecchinato et al. [40] 2014 Prospective Did not compare smokers vs. no smokers
Wang et al. [41] 2014 Cross sectional Not prospective
Meijer et al. [42] 2014 Prospective Did not report information on smoking
Canullo et al. [43] 2016 Cross sectional Not prospective
Aguilar-Salvatierra et al. [44] 2016 Prospective Did not report information on smoking
Serino et al. [45] 2015 Prospective Did not compare smokers vs. no smokers
Mangano et al. [46] 2014 Prospective Did not compare smokers vs. no smokers
Kütan et al. [47] 2015 Randomized clinical trial Did not report information on smoking
Gomes et al. [48] 2015 Prospective Did not report information on smoking
Becker et al. [49] 2015 Prospective Did not report information on smoking
Donati et al. [50] 2015 Prospective Did not report information on smoking
Pozzi et al. [51] 2015 Prospective Did not report information on peri-implantitis
Schwarz et al. [52] 2015 Cross sectional Not prospective
Krennmair et al. [53] 2016 Prospective Did not compare smokers vs. no smokers
van Velzen et al. [54] 2015 Prospective Did not compare smokers vs. no smokers
Malchiodi et al. [55] 2015 Prospective Did not compare smokers vs. no smokers
Hita-Iglesias et al. [56] 2015 Prospective Did not report information on peri-implantitis
Daubert et al. [57] 2015 Cross sectional Not prospective
Gherlone et al. [58] 2015 Prospective Sample not representative of general population
Konermann et al. [59] 2016 Cross sectional Not prospective