Table 1. | PICOS guidelines |
| Patient and population (P) | All adult patients (> 17 years) with a transverse maxillary hypoplasia requiring orthognatic surgery. |
| Intervention (I) | Segmental Le Fort I osteotomy. |
| Comparator or control group (C) | Surgically assisted rapid maxillary expansion |
| Outcomes (O) | Transverse dentoalveolar and skeletal expansion and relapse, total dentoalveolar expansion, frequency of complications and patient-related outcome measure. |
| Study design (S) | Human studies, including randomized controlled trials, controlled clinical trials and retrospective studies, with the aim of comparing transverse dental and skeletal expansion and relapse after segmental Le Fort I osteotomy compare to surgically assisted rapid maxillary expansion. |
| Focused question | Are there any differences in the transverse maxillary dentoalveolar and skeletal expansion and relapse between segmental Le Fort I osteotomy and surgically assisted rapid maxillary expansion? |
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