Table 1. | Predictors of lymphoma development in Sjögren’s syndrome |
| Clinical | Serological |
|---|---|
| Persistent parotid gland enlargement | Mixed monoclonal cryoglobulinemia |
| Splenomegaly | Low serum C4 levels |
| Lymphadenopathy | Serum or urine monoclonal bands |
| Palpable purpura | CD4 + T lymphocytopeniaa |
| Leg ulcers | Neutropeniaa |
| Peripheral neuropathy | High serum β2 microglobulina |
| Previous low-dose irradiation or chemotherapy | Low serum IgM levelsa |
| Disappearance of previously positive rheumatoid factor |
aΙndicates detected findings in the present case. |
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