Clinical Serological
Persistent parotid gland enlargement Mixed monoclonal cryoglobulinemia
Splenomegaly Low serum C4 levels
Lymphadenopathy Serum or urine monoclonal bands
Palpable purpura CD4 + T lymphocytopeniaa
Leg ulcers Neutropeniaa
Peripheral neuropathy High serum β2 microglobulina
Previous low-dose irradiation or chemotherapy Low serum IgM levelsa
Disappearance of previously positive rheumatoid factor

aΙndicates detected findings in the present case.