Table 1. | PICOS guidelines |
| Component | Description |
|---|---|
| P (problem) | Oral cancer |
| I (intervention/indicator) | Chronic inflammation around dental implants |
| C (comparison) | Comparison between patients with\without a history of oral or systemic malignancy |
| O (outcome of interest) | Oral cancer prevention\early diagnosis |
| Focus question | What is the association between oral cancer appearances around dental implants in patients with\without a history of oral or systemic malignancy? |
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