Figure 1.

Expression of laminin-332 γ2 chain and MMP-9 in high risk of malignant transformation oral lesions and oral squamous cell carcinoma (OSCC) was examined by immunohistochemistry. Scale bar = 20 μm.
A = positive control of laminin-332 γ2 chain along epithelial-stromal interface, showing a linear structure (arrow).
B = MMP-9 expression in endothelial cells of IFH (* symbol).
C = high risk oral lesion with continuous basement membrane (arrow).
D = MMP-9 citoplasmatic staining in epithelium cells.
E = OSCC well differentiated with areas of continuous basement membrane (arrows) and laminin-332 γ2 chain expression in SL.
F = epithelium citoplasmatic expression of MMP-9 in OSCC.
G = areas of invasive front with laminin-332 γ2 chain citoplasmatic expression and a cellular membrane staining in OSCC moderately differentiated (arrowhead).
H = enzyme expression in stromal cells surrounding OSCC nests.