Table 2. | The focus question development according to the PICOS study design |
| Component | Description |
|---|---|
| Problem (P) | Osteonecrosis of the jaw. |
| Intervention (I) | Dental implant placement on patients with bisphosphonate therapy. |
| Comparison (C) | Comparison between patients with intraoral and intravenous bisphosphonate therapy. |
| Outcome (O) | Bisphosphonate related osteonecrosis of the jaw. |
| Study design (S) | Randomized controlled trial. |
| Focus question | Is dental implant placement purposeful for patients using bisphosphonates? |
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