Component Description
Problem (P) Osteonecrosis of the jaw.
Intervention (I) Dental implant placement on patients with bisphosphonate therapy.
Comparison (C) Comparison between patients with intraoral and intravenous bisphosphonate therapy.
Outcome (O) Bisphosphonate related osteonecrosis of the jaw.
Study design (S) Randomized controlled trial.
Focus question Is dental implant placement purposeful for patients using bisphosphonates?