Table 1. | The focus question development according to the PICOS study design |
| Component | Description |
|---|---|
| Problem (P) | Bone resorption after tooth extraction |
| Intervention (I) | Filling alveolar socket with regenerative biomaterial |
| Comparison (C) | Comparison between efficiency of different biomaterials |
| Outcome (O) | Different dimensional changes of alveolar bone |
| Study design (S) | Random controlled trial |
| Focus question | What biomaterials in combination with stem cells and growth factors are used for socket preservation after the tooth extraction and which of those show the best results regarding alveolar dimensional changes and quality of newly formed bone? |
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