Table 2

Study	Year of publication	Study design	NOP	Materials and methods							Outcome measures
				MSFA	RBH (mm)	Type of grafting material	Membrane	Number of implants	Prosthetic solution	LOP (month)	Survival of implants (%)	Bone regeneration (%)			Biologic and mechanical complications
				MSFA	RBH (mm)	Type of grafting material	Membrane	Number of implants	Prosthetic solution	LOP (month)	Survival of implants (%)	NFB	NMT	RG	Biologic and mechanical complications
Froum et al. [16]	1998	RCT	113	113	NR	Combination of different grafting materials	e-PTFE: 79	133	NR	6 - 9	99	17 - 33	NR		NR
Froum et al. [16]	1998	RCT	113	113	NR	Combination of different grafting materials	No membrane coverage: 34	82	NR	6 - 9	96	9 - 19	NR		NR
Tarnow et al. [17]	2000	RCT, split-mouth	12	12	NR	Combination of different grafting materials	e-PTFE: 12	28	NR	7 - 13	100	26 (SD 15)	NR		NR
Tarnow et al. [17]	2000	RCT, split-mouth	12	12	NR	Combination of different grafting materials	No membrane coverage: 12	27	NR	7 - 13	93	12 (SD 8)	NR		NR
Tawil et al. [24]	2001	RCT	29	30	4 - 8	Bio-Oss®: 100%	Collagen membrane: 15	29	Fixed prostheses	22.4 (12 - 40)	93	NR			Mucosal tears: 5
Tawil et al. [24]	2001	RCT	29	30	4 - 8	Bio-Oss®: 100%	No membrane coverage: 15	32	Fixed prostheses	22.4 (12 - 40)	78	NR			Mucosal tears: 5
Wallace et al. [25]	2005	CCT	51	21	NR	Bio-Oss®: 100%; PABG: 20% and Bio-Oss®: 80%	e-PTFE: 21	46	NR	12	98	17	51	32	NR
				37			Collagen membrane: 37	83			98	18	56	26
				6			No membrane coverage: 6	6			100	12	64	24
Choi et al. [26]	2009	RCT, split-mouth	6	12	NR	Bio-Oss®: 100%	Collagen membrane: 6	NR	NR	8 (7 - 9)	NR	13^a	36^b	50^c	None
Choi et al. [26]	2009	RCT, split-mouth	6	12	NR	Bio-Oss®: 100%	No membrane coverage: 6	NR	NR	8 (7 - 9)	NR	12	55	33	Dehiscence: 1; swelling: 1
Barone et al. [27]	2013	RCT	18	18	< 5	PABG: 50%; MP3®: 50%	Collagen membrane: 9	NR	NR	6	NR	31 (SD 16)	51 (SD 19)	18 (SD 20)	SMP: 1; dehiscence: 1; haematoma: 2
Barone et al. [27]	2013	RCT	18	18	< 5	PABG: 50%; MP3®: 50%	No membrane coverage: 9	NR	NR	6	NR	28 (SD 19)	59 (SD 15)	13 (SD 12)	SMP: 2; dehiscence: 1; haematoma: 2
García-Denche et al. [28]	2013	RCT, split-mouth	109	66	4 - 7	Bio-Oss®: 100%	Collagen membrane: 66	278	Fixed prostheses or bar retention	12	96.1^d	19 (SD 6)^e	31 (SD 3)^f	49 (SD 10)^g	None
García-Denche et al. [28]	2013	RCT, split-mouth	109	69	4 - 7	Bio-Oss®: 100%	No membrane coverage: 69	278	Fixed prostheses or bar retention	12	94.2	15 (SD 5)	32 (SD 6)	56 (SD 21)	Displacement of grafting material: 4

^aP = 0.937 (nonparametric Mann-Whitney U test); ^bP = 0.026 (nonparametric Mann-Whitney U test); ^cP = 0.093 (nonparametric Mann-Whitney U test); ^dP = 0.08 (Cohen´s f2 test); ^eP = 0.52 (non-parametric Wilcoxon t-test); ^fP = 1 (non-parametric Wilcoxon t-test); ^gP = 0.6 (non-parametric Wilcoxon t-test).
CCT = controlled clinical trial; e-PTFE = expanded polytetrafluoroethylene; LOP = length of observation period; MSFA = maxillary sinus floor augmentation; NFB = newly formed bone; NMT = non-mineralised tissue; NOP = number of patients; PABG = particulated autogenous bone graft; PIMBL = peri-implant marginal bone loss; RCT = randomised controlled trial; RG = residual graft; SMP = sinus membrane perforation; SD = standard deviation.