Table 1. | PICOS guidelines |
| Patient and population (P) | Healthy adult patients with atrophy of the alveolar process receiving lateral alveolar ridge augmentation with an autogenous bone block graft prior to implant placement. |
| Intervention (I) | Barrier membrane coverage. |
| Comparator or control group (C) | No barrier membrane coverage. |
| Outcomes (O) | Primary outcome measures included survival of implants and suprastructures. Secondary outcome measures included peri-implant marginal bone loss, two-dimensional width changes, three-dimensional volumetric width changes, bone regeneration, PROM, biological and mechanical complications. |
| Study design (S) | Randomised controlled trials. |
| Focused question | Are there any differences in implant treatment outcome following lateral alveolar ridge augmentation with an autogenous bone block graft alone with or without barrier membrane coverage? |
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