Author Type of surgery Graft description Type of result measurement Outcomes Complications
Schwarz et al. [19] Lateral alveolar; ridge augmentation Tooth root (block) CBCT -Gain in ridge width:
tooth root 5.53 (SD 1.88) mm; bone 3.93 (SD 1.41) mm;
P = 0.014
-Graft resorption:
tooth root 0.13 (SD 0.97) mm; bone 1.03 (SD 1.15) mm;
P = 0.029 		In both groups after 26 weeks screw head was exposed in one patient, but not associated with any signs of wound infection
Pang et al. [31] Alveolar bone augmentation Autogenous demineralized dentin (particulate) Resin templates and periodontal probe, histomorphometric analysis, "Osstell™ ISQ" tool for implant stability -Vertical bone gain:
DDM 5.38 (SD 2.65) mm; Bio-Oss® 6.56 (SD 3.54) mm;
P = 0.337
-Percentage of newly formed bone:
DDM 31.24 (SD 13.87)%; Bio-Oss® 35 (SD 19.33)%;
P = 0.606
-Percentage of residual graft material.
DDM 8.95 (SD 6.15)%; Bio-Oss® 17.08 (SD 16.57)%;
P = 0.245
-ISQ:
DDM 72.8 (SD 10.81); Bio-Oss® 70 (SD 12.86); P = 0.755 		No registered complications
Li et al. [32] Alveolar bone augmentation Autogenous demineralized dentin (particulate) + membrane + PRF Panoramic and periapical radiography, "Osstell™ ISQ" tool for implant stability - ISQ:
After surgery: Bio-Oss® 54.1 (SD 13); DDM 53.6 (SD 11.9);
P = 0.14
After 6 months: Bio-Oss® 78.1 (SD 4.2); DDM 77.6 (SD 7.9);
P = 0.11
After 18 months: Bio-Oss® 80.2 (SD 4.3); DDM 79.5 (SD 6);
P = 0.09
- Marginal bone resorption:
After 6 months: Bio-Oss® 1.8 (SD 0.1) mm; DDM 1.7 (SD 0.3) mm; P = 0.25
After 18 months: Bio-Oss® 2 (SD 0.5) mm; DDM 1.9 (SD 0.6) mm; P = 0.18 		Failed osseointegration and infection in one implant in both groups
Santos et al. [33] Alveolar ridge preservation Autogenous mineralized dentin (particulate) CBCT, periapical radiography, histomorphometric analysis, "Osstell™ ISQ" tool for implant stability, "VAS" scale - Primary ISQ:
MDM 77.1 (SD 6.9); xenograft 77 (SD 5.9); P = 0.807
- Secondary ISQ after 2 months:
MDM 81.8 (SD 5.1); xenograft 80.1 (SD 3.8); P = 0.054
- Percentage of newly formed bone:
MDM 47.3 (SD 14.8)%; xenograft 34.9 (SD 13.2)%; P = 0.001
- Percentage of remaining bone substitute:
MDM: 12.2 (SD 7.7)%; xenograft: 22.1 (SD 10.9)%; P = 0.001
- Reported pain:
MDM: 10/26; xenograft: 10/26; P = 0.904 		- Hematoma:
MDM 26.5%; xenograft 18.8%; P = 0.596
- Dehiscence:
MDM 38.2%; xenograft 46.9%; P = 0.549
- Membrane exposure:
MDM 11.8%; xenograft 12.5%; P = 0.968
- Graft exposure:
MDM 0%; xenograft 0%
Kim et al. [34] Maxillary sinus floor lift Autogenous demineralized dentin (particulate) Panoramic radiography - Vertical bone gain:
DDM 4.89 mm; synthetic bone 6.22 mm; P = 0.46
- Bone resorption after 1 year:
DDM 0.76 mm; synthetic bone 0.53 mm; P = 0.57 		Failed osseointegration of one implant in synthetic bone group
Korsch and Peichl [35] Lateral alveolar; ridge augmentation Partially demineralized dentin block (particulate) CBCT, "Osstell™ ISQ" tool for implant stability - ISQ:
BST 74.7; TST 73.3
- Horizontal hard tissue loss (after 3months):
BST (1 case) 0.5 mm; TST (1 case) 1 mm.
- Integrity of the buccal lamella (after 3 months):
TST - did not happen in most cases; BST - happen in most cases 		- Wound dehiscences:
BST 2 of 31; TST 1 of 28; P = 0.615
- Inflammations:
BST 3 of 31; TST: 0 of 28; P = 0.091
Xiao et al. [36] Alveolar bone augmentation Autogenous dentin (particulate) + xenograft + collagen membrane + CGF CBCT - Vertical bone gain:
dentin 2.91 (SD 3.75) mm; bone 2.79 (SD 3.95) mm; P = 0.886
- Vertical bone resorption:
dentin 0.94 (SD 1.43) mm; bone 1.72 (SD 0.84) mm; P = 0.114
- Horizontal bone resorption at 2, 4 and 6 mm:
Dentin: 2.41 (SD 2.11) mm; bone: 3.79 (SD 2.77) mm;
P = 0.431
Dentin: 1.49 (SD 2.41) mm; bone: 1.94 (SD 1.84) mm;
P = 0.283
Dentin: 1.2 (SD 153) mm; bone: 1 (SD 0.64) mm; P = 0.664 		No registered complications

DDM = demineralized dentin matric; MDM = mineralized dentin matric; TST = tooth-shell technique; BST = bone-shell technique; CBCT = cone-beam computed tomography; ISQ = implant stability quotient.