Study New bone formation Bone height
(mm) 		ISQ Schneiderian membrane thickness
(mm) 		Follow-up
Nizam et al. [17] Test group (with PRF) 21.38 (SD 8.78)%
vs. Control group (without PRF) 21.25 (SD 5.59)%
(P = 0.96) 		Test group (with PRF) 13.6 (SD 1.09)
vs. Control group (without PRF) 13.53 (SD 1.2);
(P = 0.88) 		NR NR 6 months follow-up
Pichotano et al. [18] Test group (with PRF) 44.58 (SD 13.9)%
vs. Control group (without PRF) 30.02 (SD 8.42)%
(P = 0.0087) 		Residual graft in the control group 13.75 (SD 9.99)%
vs. Test group 3.59 (SD 4.22)
(P = 0.0111) 		Test group
60.9 (SD 9.35)
vs. Control group 75.13 (SD 5.69)
(P = 0.0003) 		NR Immediately after implant placement,
4 and 8 months after sinus augmentation
Salimzade et al. [19] NR NR NR Test group: baseline 2.17, after 2 months 1.77
vs. Control group: baseline 1.85,
after 2 months 2.54;
(P = 0.2) 		2 months follow-up
de Almeida Malzoni et al. [20] Test group (L-PRF + DBBM) 18.35
(SD 5.62)%
vs. Control group (DBBM) 12.95
(SD 5.33)%
(P = 0.0135) 		Test group: DBBM4 0.58 cm3 - DBBM8 0.72 cm3
vs. Control group: mean t1 - t2 0.48 cm3 		Test group L-PRF + DBBM4 to
L-PRF + DBBM8 72.19 (SD 5.43)
vs. Control group 75.56 (SD 4.6)
(P ≤ 0.0001) 		NR 1-year follow-up
Shiezadeh et al. [21] Group A (with PRF) 43.25%
vs. Group B (without PRF) 38.25%
(P = 0.087) 		Group A (with PRF) 2.74 mm
vs. Group B (without PRF) 2.72 mm 		NR NR Average of 33 months follow-up

ISQ = implant stability quotient; NR = not reported; PRF = platelet rich fibrin; L-PRF = platelet rich fibrin; DBBM = deproteinized bovine bone mineral; SD = standard deviation.