A = Type I collagen expression was higher in mild and moderate OED than moderately differentiated OSCC (P = 0.04; P = 0.03, respectively). Severe OED had a lower expression than moderate OED (P = 0.01) and well differentiated OSCC lesions (P = 0.02).
B = Low-risk had a higher expression than high-risk (P = 0.03) and moderately differentiated OSCC (P = 0.01). High-risk cases had a lower collagen expression than well-differentiated OSCC (P = 0.02).
C = Moderate OED cases with more collagen expression than high-risk (P = 0.01). Severe OED showed less protein than low-risk (P = 0.03).