Table 1

Study	Time of onset (days)/number of cycle	Symptoms	History of recurrent aphthous stomatitis	Keratinized/non-keratinized mucosa	Steroid use	Clinical outcome/time	Recurrence	Panitumumab dose reduction or discontinuation (due to oral complications)
Gomes et al. [8]	8/1^st - 2^nd	Pain, feeding discomfort	None	-/+	Acetonide triamcinolone (topical)	Resolved/complete resolution in a mean time of 1 week (1 to 3 weeks) after the initial oral management	Yes	Dose reduction in 2 patients. Drug discontinuation in 1 patient
	7/1^st - 2^nd			+^a/+	No		Yes
	11/1^st - 2^nd			-/+	No		No
	10/4^th			+^b/+	Clobetasol propionate (topical)		No
	10/1^st - 2^nd			-/+	Clobetasol propionate (topical), prednisone (per os)		Yes
	7/1^st - 2^nd			+^a,c/+	Clobetasol propionate (topical)		Yes
	11/rechallenge of therapy			+^d,e/+	No		No
Thermos et al. [9]	10/1^st	Multiple oral aphthae	None	+^a/+	Prednisolone (topical)	Resolved/ 1 week	Yes	Drug discontinuation
Our case	8/14^th	Pain	None	-/+	Dexamethasone (topical)	Resolved/ 1 week	No	No

Lesions on keratinized mucosa: ^atip of the tongue; ^bgingiva; ^calveolar mucosa at mandibular torus; ^ddorsum of the tongue; ^eherpes infection.