Question
number
Defined question
Q1 Is it clear in the study what is the "cause" and what is the "effect" (i.e. there is no confusion about which variable comes first)?
Q2 Was there a control group?
Q3 Were participants included in any comparisons similar?
Q4 Were the participants included in any comparisons receiving similar treatment/care, other than the exposure or intervention of interest?
Q5 Were there multiple measurements of the outcome, both pre and post the intervention/exposure?
Q6 Were the outcomes of participants included in any comparisons measured in the same way?
Q7 Were outcomes measured in a reliable way?
Q8 Was follow-up complete and if not, were differences between groups in terms of their follow-up adequately described and analysed?
Q9 Was appropriate statistical analysis used?