Table 1. | Focus question development based on the PICO framework |
| Population (P) | Patients undergoing orthodontic treatment with maxillary first premolar extraction and canine distalization |
| Intervention (I) | Laser-assisted corticotomy |
| Comparison (C) | Conventional orthodontic treatment without corticotomy |
| Outcome (O) | Acceleration of maxillary canine distalization |
| Focus question | Does laser corticotomy during orthodontic treatment accelerate maxillary canine distalization after first premolar extraction? |
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