A – D = cell adhesion 3h after cell plating. E – H = appearance of the colonized implants at day 28.
Cell adhesion: 3h after plating, cells are seen as darker points on the implant surface at low magnification (A, B); at a high magnification (C, D), cells showed a central area and cytoplasmic extensions which adapted to the underlying rough surface.
At day 28, the implants surface was completely covered by a cell layer as seen in low magnification images (E, F), and Implant II showed a thicker cell layer; at a higher magnification, Implant I showed a continuous cell layer, whereas Implant II exhibited a fibrilar cell layer reflecting a more complex organization.