First author Country Study Demographics Sex
Year of
publication
Study design No. of
subjects
Number
with OI
Age range
(years)
Mean age
(years)
Median age
(years)
M F
Maines Italy 2012 Retrospective
Cohort
102 102 3.1 - 23.4 12 x 47 55
Brown Australia 2008 Retrospective
Cohort
42 37 X 8.25 x 28 14
Malmgren Sweden 2008 Retrospective
Cohort
64 64 0.2 - 20.9 8.1 x x x
Chahine Canada 2008 Retrospective
Cohort
278 221 X x 14.7 142 136
Schwartz Schwartz 2008 Case series 15 15 2 - 16 x x 11 4

OI = osteogenesis imperfecta; X = data not stated in published study; M = male; F = female.