Study Year of
publication
Number of
patients
Materials and methods Outcome measures
TMD
(mm)
Evaluation
methods
Follow-up Transverse skeletal
expansion
Transverse skeletal
relapse
Dental arch
expansion
Dental arch
relapse
Mean (SD), mm Mean (SD), mm Mean (SD), mm Mean (SD), mm
Del Santo et al. [25] 2000 20 NR Dental cast
X-ray
15 months
(6 - 31)
Region PO - PD Region PD - FFU Region PO - PD Region PO - FFU NR
BG 0.7 (4.4) BG 0.7 (4.7) ICD 3.2 (3.3)a ICD 2.4 (1.9)b
BAG 1.2 (4.4) BAG 1.2 (4.1) IPMD1 3.5 (2.4)b
ICD 3.2 (3.3)a ICD 0.5 (3.3) IPMD2 4.9 (3.9)b
IMD 2.2 (4.2)a IMD -0.4 (3) IMD 2.2 (4.2)a IMD1 5 (3.2)b
BM 0.5 (1.4) IMD2 4.1 (3.7)a
Ploder et al. [26] 2009 20 NR Dental cast
X-ray
3 months Region PO - PD NR Region PO - PD NR
ICD 3.4 (2) ICD 4.2 (1.8)
IPMD1 3.6 (1.8) IPMD1 5 (2)c
IPMD2 3.3 (1.4) IPMD2 4.7 (2)c
IMD1 3.2 (1.5) IMD1 4.3 (1.7)c
IMD2 2.2 (1.8) IMD2 3.6 (1.3)
Seeberger et al. [27] 2011 19 > 4 CT-scan 3 months Region PO - PD NR Region PO - PD NR
IPRD 2.9 (1.8)d IPD 4.8 (1.6)d
IMRP 2.6 (2.1)d IMD 4.9 (1.3)d
IMFD 2.7 (1.2)d

aP-value < 0.05 (paired t-test), bP-value < 0.01 (paired t-test), cP-value < 0.05 (statistical test as not reported), dP-value < 0.05 (Wilcoxon signed rank test).
BAG = biantegonial; BG = bigonial; CT = computed tomography; FFU = final follow-up; ICD = inter-canine distance; IMD = inter-molar distance; IMD1 = first inter-molar distance; IMD2 = second inter-molar distance; IPD = inter-premolar distance; IPMD1 = first inter-premolar distance; IPMD2 = second inter-premolar distance; IMFD = inter-mandibular mental foramen distance; IMRP = inter-molar root distance; IPRD = inter-premolar root distance; PD = post-distraction; PO = preoperative; NR = not reported; SD = standard deviation; TMD = transverse mandibular deficiency.