Subgroup/study Bio material VR
(mm)
HR
(mm)
RG
(%)
NFB
(%)
OP
(months)
Autogenous materials
Das et al. [32] PRF -1.55 NM NM NM 6
Hauser et al. [33] PRF -0.98 NM NM NM 2
Joshi et al. [42] Autogenous tooth graft -0.28 -0.15 NM NM 4
Allogenic materials
Thakkar et al. [30] DFDBA -1.38 -1.36 NM NM 6
Wood and Mealey [34] FDBA NM NM 25.42 24.63 5
DFDBA NM NM 8.88 38.42 5
Xenogenic materials
Gholami et al. [35] Bio-Oss® -1.07 NM 20.62 27.35 7.5
Barone et al. [36] Endobon NM NM NM 28.5 6
Bio-Oss® NM NM NM 31.4 6
Kotsakis et al. [37] Anorganic bovine bone mineral -0.88 -1.39 NM NM 5
Mahesh et al. [38] Bio-Oss® NM NM 25.60 22.2 5
Synthetic materials
Das et al. [32] β-TCP -0.99 NM NM NM 6
Gholami et al. [35] NCHA -0.93 - 13.68 28.63 7.5
Kotsakis et al. [37] Calcium phosphosilicate -0.83 -1.26 NM NM 5
Mahesh et al. [38] NovaBone® NM NM 17.40 47.15 5
Canullo et al. [40] Mg-e HA NM NM 40.82 31.85 4
Mg-e HA NM NM 26.28 41.32 12
Joshi et al. [42] β-TCP -1.72 -1.45 NM NM 4
Mixed materials
Thakkar et al. [30] PRF + DFDBA -1.08 -0.75 NM NM 6
Baniasadi and Evrard [31] PRF + DFDBA -0.72 NM NM NM 3
Mayer et al. [41] Biphasic calcium sulphate + β-TCP + HA NM 0.03 15.99 NM 4
Pang et al. [43] Bio-Oss® + Bio-Gide® -1.54 -1.84 NM NM 6
Natto et al. [44] FDBA + CMS -0.30 -1.21 NM NM 4
FDBA + CS -0.79 -1.47 NM NM 4
Nam et al. [45] DBM + synthetic olygopeptide NM NM NM 10.4 6

PRF = platelet rich fibrin; DFDBA = demineralized freeze-dried bone allograft; FDBA = freeze-dried bone allograft; TCP = tricalcium phosphate; HA = hydroxyapatite; DBM = demineralised bone matrix; NM = not mentioned.