A = ALP activity in culture medium of porcine femur bone explants (n = 3) stimulated for 7 days with DHT, Aln or a combination of both.
B and C = 2D µCT reconstruction and (C) µCT analysis of trabecular bone parameters and bone strength of porcine bone explants (n = 3) stimulated with DHT and Aln after 28 days compared to a non-stimulated controls;
D = analysis of trabecular bone parameters of human osteoarthritic femur bone explants stimulated with DHT (n = 65) and Aln (n = 62) compared to non-stimulated controls.
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