A = Histological section of F20 treated defect.
B = High magnification of the boxed area in (A), showing an irregular defect border.
C = High magnification of boxed area of (A), showing Bio-Oss^® granules completely surrounded by new bone.
D = F20 treated defect where Bio-Oss^® granules extending into the bone marrow cavity.
E = Histological section of a F50 treated defect showing the Bio-Oss^® granules within the defect.
F and G = High magnification of a F20 treated defect showing a void where osteoid tissue and osteoblasts lined the newly formed bone.
G and H = Osteoclast-like cells lined the surface of Bio-Oss^® granules.
Dashed line = defect border; dashed oval = osteon; nb = new bone; cb = cortical bone; bo = Bio-Oss^®; nmt = non-mineralized tissue; closed arrowhead = osteoblasts; bm = bone marrow; ost = osteoid tissue; open arrowhead = osteoclast-like cells.