Table 2

Parameters	Category	NM	OSF	OSF + OSCC	P-value
Parameters	Category	N (%)	N (%)	N (%)	P-value
Percentage positivity	0 = no positive cells	1 (10)	10 (33.3)	21 (70)	< 0.001^a
	1 = 0 to 25%	4 (40)	20 (66.6)	9 (30)
	2 = 26 to 50%	5 (50)	-	-
	3 = > 50%	-	-	-
Pattern	Absent	1 (10)	10 (33.3)	21 (70)	0.001^a
	Cytoplasm	-	-	-
	Nuclear	9 (90)	20 (66.6)	9 (30)
Layers	0 = absent	1 (10)	10 (33.3)	-	0.233
	1 = basal/parabasal	9 (90)	20 (66.6)	-
	2 = spinous	-	-	-
	3 = superficial layer	-	-	-

Comparison of IHC expression of PTEN among groups using Pearson's Chi-square and Fisher exact test
^aStatistically significant at level P < 0.05, Pearson's Chi-square and at level P < 0.05, Fischer exact test.
NM = normal mucosa; OSF = oral submucous fibrosis; OSCC = oral squamous cell carcinoma; N = number; IHC = immunohistochemical; PTEN = phosphatase and tensin homologue.