Checklist Yes No N/A
1. Was the study question or objective clearly stated? X
2. Were eligibility/selection criteria for the study population prespecified and clearly described? X
3. Were the participants in the study representative of those who would be eligible for the test/service/intervention in the general or clinical population of interest? X
4. Were all eligible participants that met the prespecified entry criteria enrolled? X
5. Was the sample size sufficiently large to provide confidence in the findings? X
6. Was the test/service/intervention clearly described and delivered consistently across the study population? X
7. Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? X
8. Were the people assessing the outcomes blinded to the participants' exposures/interventions? X
9. Was the loss to follow-up after baseline 20% or less? Were those lost to follow-up accounted for in the analysis? X
10. Did the statistical methods examine changes in outcome measures from before to after the intervention?
Were statistical tests done that provided p values for the pre-to-post changes? 		X
11. Were outcome measures of interest taken multiple times before the intervention and multiple times after the intervention (i.e., did they use an interrupted time-series design)? X
12. If the intervention was conducted at a group level (e.g., a whole hospital, a community, etc.) did the statistical analysis take into account the use of individual-level data to determine effects at the group level? X

N/A = not applicable.