Study Follow-up
(month) 		Total no. of implants placed Implant site of placement Implant survival (%) Insertion torque
(Ncm) 		P-value ISQ P-value PIBL
(mm) 		P-value PD
(mm) 		P- value PI
(%/Silness and Löe) 		P-value FMPS
(%) 		P-value BOP
(%) 		P-value
Test Control Test Control Test Control Test Control Test Control Test Control Test Control Test Control
M (SD) M (SD) M (SD) M (SD) M (SD) M (SD) M (SD) M (SD) M (SD) M (SD)
Eshkol-Yogev et al. [16] 3 32 Posterior maxilla 100 100 45
(range 18 to 80) 		50
(range 45 to 50) 		≥ 0.05 74.4 (6) 77.6 (3.6) 0.097 0.5 (0.4) 0.5 (0.7) 0.1 NR NR NR NR NR NR NR NR NR NR NR NR
Li Manni et al. [17] 12 34 Posterior maxilla 100 100 ≤ 45 ≤ 45 NR NR NR NR 0.22 (0.3) 0.42 (0.67) 0.25 NR NR NR NR NR NR 7.91 (8.31) 6.35 (6.29) 0.54 17.6 29.4 0.42
Tokuc and Kan [18] 12 40 Anterior mandible 100 100 40.5 (SD 10.37); range 25 to 50 39.25 (SD 9.77); range 25 to 50 0.075 8 weeks: 77.1 (5.42) 8 weeks: 78.4 (6.96) 0.2 0.58 (0.36) 0.91 (0.59) < 0.01 1.67 (0.95) 1.61 (0.98) 0.886 0.47 (0.82) 0.52 (0.83) 0.59 NR NR NR NR NR NR
Hurtgen et al.* [19] 36 26 Posterior maxilla 100 100 ≤ 45 ≤ 45 NR NR NR NR 0.39 (0.42) 0.23 (0.43) 1.00 2.88 (0.56) 3.05 (0.7) 0.53 19.44 (25.46) 18.18 (27.34) 0.91 15.28 (16.37) 26.16 (21) 0.17 33.3 16.7 0.64
60 25 Posterior maxilla 100 100 ≤ 45 ≤ 45 NR NR NR NR 0.38 (0.39) 0.29 (0.58) 0.49 3.32 (0.531) 3.36 (0.531) 0.83 19.7 (26.69) 30.95 (32.59) 0.36 20.37 (15.04) 30 (23.03) 0.24 100 64.3 0.08
Tokuc and Kan [20] 60 38 Anterior mandible 100 100 38.8 (SD 13.1);
range 25 to 50 		40 (SD 9.4);
range 25 to 50 		0.888 NR NR NR 0.71 (0.69) 1.03 (0.86) < 0.01 1.85 (0.8) 1.84 (0.83) 0.839 0.44 (0.54) 0.39 (0.51) 0.719 NR NR NR NR NR NR

M (SD) = mean (standard deviation); NR = not recorded; PD = probing depth; BOP = bleeding on probing; PIBL= peri-implant bone level; FMPS = full mouth plaque score; ISQ = implant stability quotient; PI = plaque index.
*Hurtgen et al. [19] is a follow-up study of Li Manni et al. [17] with follow-up periods of 36 and 60 months.