Study Year of
publication 		Patients Materials and methods Follow-up
after loading (months) 		Primary
outcome measures 		Secondary
outcome measures
ARW
(mm) 		Split-crest Site Implant Graft/
membrane 		Implant healing Prosthetic solution Survival (%) IS PIMBL
(mm) 		GARW (mm) BTC
Prosthesis Implant
González-García et al. [21] 2011 8 3 - 4 8 Anterior/posteior 33 Autogeous bone/Laddec®
+ membrane 		4 months NR 28.3 NR 100 69.5 ISQ 2-years NR None
0.54
Garcez-Filho et al. [22] 2015 21 3 - 5 26 Posterior 40 Bio-Oss® 6 - 8 weeks SC: 20
FPD: 19 		120 97 97 NR 6 months 10 years NR Retained screw/SC change: 6
0.47 1.93
Santagata et al. [23] 2015 13 4.67 (3.5 - 7) 13 Anterior/posterior 33 Putty® 4 months NR 36 NR 97 NR NR 3.5
(1.45 - 4.9) 		None
Albanese et al. [24] 2017 10 2.75 (2.5 - 4) 10 Anterior 45 Fresh frozen bone chips 8 months NR 12 NR 97.8 35 Ncm 1.19 3.25 Oedema,
pain: 9%

ARW = alveolar ridge width; BTC = biological and technical complications; FPD = fixed partial denture; IS = implant stability; ISQ = implant stability quotient; NR = not reported; PIMBL = peri-implant marginal bone loss; SC = single crowns.