No. Gene Protein Biological function
1. ANXA1* Annexin A1 This protein plays a role in cellular response to vascular endothelial growth factor stimulus.
2. THBS1* Thrombospondin-1 This protein induce blood vessel endothelial cell migration, has a positive regulation of fibroblast migration, positive regulation of angiogenesis, positive regulation of cell population proliferation.
3. CALR* Calreticulin This protein has a positive regulation of endothelial cell migration.
4. COL3A1* Collagen alpha-1(III) chain It acts in collagen fibril organization, wound healing, cell-matrix adhesion.
5. HSPG2* Basement membrane-specific heparan sulfate proteoglycan core protein Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization.
6. FBN1* Fibrillin-1 Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin.
7. COL4A1* Collagen alpha-1(IV) chain Type IV collagen is the major structural component of glomerular basement membranes, forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen.
8. SERPINE1* Plasminogen activator inhibitor 1 It is required for stimulation of keratinocyte migration during cutaneous injury repair.
9. CST3* Cystatin-C Cystatin acts as a regulator of tissue remodeling, has a negative sense to regulation of collagen catabolic process and regulation of blood vessel remodeling.
10. DPP4* Dipeptidyl peptidase 4 In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM.
11. KRT1* Keratin, type II cytoskeletal 1 This protein plays a role in keratinization and regulation of angiogenesis.
12. CHI3L1* Chitinase-3-like protein 1 Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. Play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.
13. LRP1* Prolow-density lipoprotein receptor-related protein 1 Act as an inducer of vascular associated smooth muscle cell migration.
14. MMP2* 72 kDa type IV collagenase Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture.
15. GPNMB* Transmembrane glycoprotein NMB It has a sense in regulation of angiogenesis, regulation of tissue remodeling.
16. NRP1* Neuropilin-1 Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system.
17. SERPING1 Plasma protease C1 inhibitor Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins.

*Proteins cells are also involved in other biological processes.