No.
|
Gene
|
Protein
|
Biological function
|
1.
|
CALR*
|
Calreticulin
|
This protein is involved in regulation of meiotic nuclear division, regulation of transcription, DNA-templated, protein localization to nucleus, protein export from nucleus, has a positive influence to regulation of dendritic cell chemotaxis.
|
2.
|
COL3A1*
|
Collagen alpha-1(III) chain
|
Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
|
3.
|
COL4A1*
|
Collagen alpha-1(IV) chain
|
This protein is involved in brain development, neuromuscular junction development.
|
4.
|
LRP1*
|
Prolow-density lipoprotein receptor-related protein 1
|
Modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.
|
5.
|
S100A6
|
Protein S100-A6
|
This protein has a function as calcium sensor and modulator, contributing to cellular calcium signaling. Plays a role in axonogenesis and signal transduction.
|
6.
|
SERPINE2*
|
Glia-derived nexin
|
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
|