Q1
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Was true randomization used for assignment of participants to treatment groups?
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Q2
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Was allocation to treatment groups concealed?
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Q3
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Were treatment groups similar at the baseline?
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Q4
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Were participants blind to treatment assignment?
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Q5
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Were those delivering treatment blind to treatment assignment?
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Q6
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Were outcomes assessors blind to treatment assignment?
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Q7
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Were treatment groups treated identically other than the intervention of interest?
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Q8
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Was follow up complete and if not, were differences between groups in terms of their follow up adequately described and analysed?
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Q9
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Were participants analysed in the groups to which they were randomized?
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Q10
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Were outcomes measured in the same way for treatment groups?
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Q11
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Were outcomes measured in a reliable way?
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Q12
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Was appropriate statistical analysis used?
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Q13
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Was the trial design appropriate, and any deviations from the standard RCT design (individual randomization, parallel groups) accounted for in the conduct and analysis of the trial?
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