Study Last
follow-up
(months) 		Population Patients
(n) 		Sockets
(n) 		Age
(years) 		Gender
Test Control Test Control Total
Harsha et al. [19] 3 Patients undergoing bilateral mandibular third molar extractions 50 50 50 NR NR NR NR
Cruz et al. [20] 3 Patients requiring posterior tooth extractions 26 13 13 43.8 8 males;
5 females 		6 males;
7 females 		14 males;
12 females
Sezavar et al. [21] 2 Patients who underwent tooth extractions and were planning for dental implant placement 3 10 10 41 NR NR 2 males;
1 female
Degala et al. [22] 3 Patients undergoing bilateral surgical removal of impacted mandibular third molars 30 30 30 31.5 NR NR 16 males;
14 females
Chauhan et al. [23] 3 Bilateral similarly impacted mandibular third molars 30 30 30 18 to 40 NR NR NR
Saifi et al. [24] 4 Patients requiring all four first premolar extractions 15 30 30 21.8
(SD 2.86) 		NR NR 6 males
9 females

N = number; NR = not reported; SD = standard deviation.