Question number
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Defined question
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Q1
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Were the two groups similar and recruited from the same population?
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Q2
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Were the exposures measured similarly to assign people to both exposed and unexposed groups?
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Q3
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Was the exposure measured in a valid and reliable way?
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Q4
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Were confounding factors identified?
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Q5
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Were strategies to deal with confounding factors stated?
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Q6
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Were the groups/participants free of the outcome at the start of the study (or at the moment of exposure)?
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Q7
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Were the outcomes measured in a valid and reliable way?
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Q8
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Was the follow-up time reported and sufficient to be long enough for outcomes to occur?
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Q9
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Was follow-up complete, and if not, were the reasons to loss to follow-up described and explored?
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Q10
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Were strategies to address incomplete follow up utilized?
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Q11
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Was appropriate statistical analysis used?
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