Primary outcome measures
Survival of suprastructures. Estimated by subtracting of failed suprastructures, which is defined as a complete loss of the suprastructure due to technical and/or biological complications
Survival of implants. Estimated by subtracting of failed implants, which is defined as mobility of previously clinically osseointegrated implants or removal of non-mobile implants due to progressive peri-implant marginal bone loss or infection
Secondary outcome measures
Duration of surgery. Estimated in minutes
Implant stability quotient. Estimated by magnetic resonance frequency analysis, percussion test or reverse torque test
Peri-implant marginal bone loss including bleeding on probing, probing depth, mucosal recession, clinical attachment level and peri-implant marginal bone level as evaluated by clinical or radiographic measurements
Surgical, biological, and technical complications
Endo-sinus bone gain as evaluated by histological or radiographic measurements
Bone density as evaluated by computed tomography scan and Hounsfield units scale or cone-beam computed tomography scan and grayscale levels
Patient-reported outcome measures