Time Group Mean
change 		95% CI P
(change = 0) 		P
(intervention)a 		P
(time point)a
Week 1 Le Fort I osteotomy
(maxilla) 		Intervention 1 -1.98 -3.52; -0.45 0.01 0.82 -
Intervention 2 -1.85 -3.18; -0.52 0.01
Control -2.89 -4.02; -1.76 0.00
Week 1 Bilateral
sagittal split osteotomy
(mandible) 		Intervention 1 -2.34 -3.66; -1.01 0.00 0.58 -
Intervention 2 -1.74 -3.42; -0.06 0.04
Control -1.13 -2.67; 0.4 0.15
Week 1 Bimaxillary
(double) 		Intervention 1 -2.68 -3.33; -2.04 0.00 0.09 0.72
Intervention 2 -2.74 -3.37; -2.12 0.00
Control -3.03 -3.69; -2.37 0.00
Week 3 Le Fort I osteotomy
(maxilla) 		Intervention 1 -2.5 -4.03; -0.97 0.00 0.69 -
Intervention 2 -2.9 -4.23; -1.57 0.00
Control -2.64 -3.77; -1.5 0.00
Week 3 Bilateral
sagittal split osteotomy
(mandible) 		Intervention 1 -2.58 -3.9; -1.25 0.00 0.28
Intervention 2 -1.4 -3.08; 0.28 0.1
Control -1.38 -2.92; 0.15 0.08
Week 3 Bimaxillary
(double) 		Intervention 1 -3.24 -3.88; -2.6 0.00 0.11 0.02
Intervention 2 -3.03 -3.65; -2.4 0.00
Control -3.65 -4.3; -2.99 0.00
Week 8 Le Fort I osteotomy
(maxilla) 		Intervention 1 -2.15 -3.77; -0.53 0.01 0.02 -
Intervention 2 -1.66 -2.99; -0.34 0.01
Control -2.59 -3.72; -1.46 0.00
Week 8 Bilateral
sagittal split osteotomy
(mandible) 		Intervention 1 -1.26 -2.59; 0.06 0.06 0.45 -
Intervention 2 -0.36 -2.04; 1.32 0.67
Control -1.4 -2.93; 0.13 0.07
Week 8 Bimaxillary
(double) 		Intervention 1 -2.4 -3.04; -1.77 0.00 0.27 0.08
Intervention 2 -3.22 -3.84; -2.59 0.00
Control -3.48 -4.14; -2.82 0.00

aStatistically significant at level P < 0.05 (Wald test).
CI = confidence interval.