Stromal characteristics PGCG CGCG P-valuea
Prominent hemorrhage or hemosiderin 55.55% 85.72% 0.162
Prominent bone or osteoid formation 11.11% 85.72% 0.001
Prominent fibrosis 44.44% 64.29% 0.417
Prominent cellularity 77.78% 92.85% 0.538
Foci of acute or chronic inflammatory cells 33.33% 14.28% 0.343
Type of stromal cells Spindle 55.55% 78.57% 0.363
Ovoid 45.45% 21.43%
Type of nuclei in giant cells Vesicular 44.41% 35.71% 1
Solid 55.59% 64.29%
Pattern of distribution of giant cells Diffuse 100% 71.42% 0.127
Focal 0% 28.58%
Separation of giant cells from stroma 66.67% 64.29% 1

aStatistically significant at the level P < 0.05 (Fisher-exact test).
CGCG = central giant cell granuloma; PGCG = peripheral giant cell granuloma.