SRM3 with A-PRF
(No. 39) 		SRM3 with NSH
(No. 40) 		P-valuea
Surgical time (min) Mean (SD) 11.6 (4.1) 11 (3.8) 0.54
Range 6.2; 22.4 5.2; 22.4
Intraoperative Tooth sectioning 26 30 0.72
Visualization of IAN 5 4 1.00
Days of additional analgesic Mean (SD) 4.6 (2.5) 4.9 (2.8) 0.64
Infection treated with antibiotic 5 4 1.00

aStatistically significant at P < 0.05 (chi-square tests for categorical data and t-test for continuous data).
A-PRF = advanced platelet-rich fibrin; IAN = inferior alveolar nerve; NSH = natural socket healing; SD = standard deviation; SRM3 = surgical removal of an impacted mandibular third molar.